Which of the following describes the gender most prone to CINV?

The gender most prone to Chemotherapy-Induced Nausea and Vomiting (CINV) is female. Research consistently shows that women experience CINV more frequently and with greater severity than men. This susceptibility is often attributed to hormonal differences, particularly the influence of estrogen and progesterone on the central nervous system and gastrointestinal tract. Additionally, psychological factors such as anxiety and fear of nausea, which are typically more acute in women undergoing chemotherapy, can exacerbate the incidence and intensity of CINV.

Understanding this predisposition is crucial for healthcare providers when developing management strategies for CINV. Recognizing that females are at greater risk allows for more targeted prevention and treatment protocols, which may include the early use of antiemetics tailored to this demographic. This knowledge also emphasizes the importance of monitoring and supporting female patients through their chemotherapy regimen to mitigate these side effects effectively.