Which of the following is a common selective estrogen receptor modulator (SERM)?

Bazedoxifene is a common selective estrogen receptor modulator (SERM). SERMs are compounds that can selectively stimulate or inhibit estrogen receptors in different tissues. Bazedoxifene is specifically used in postmenopausal women for the treatment of osteoporosis and is known for its ability to mimic estrogen's beneficial effects on bone while opposing its effects on breast and uterine tissues.

The other options presented are not SERMs. For instance, Abiraterone is primarily used in the treatment of prostate cancer by inhibiting androgen production. Ketoconazole is an antifungal medication but also has some off-label uses for treating certain types of cancer by inhibiting steroidogenesis. Orteronel is also an androgen synthesis inhibitor, similar to abiraterone, used in treating prostate cancer.

The distinction of Bazedoxifene as a SERM is crucial for understanding its therapeutic applications, particularly regarding hormonal therapies and managing conditions influenced by estrogen.