Which of the following is NOT a characteristic of LHRH antagonists?

LHRH (luteinizing hormone-releasing hormone) antagonists are a class of drugs that inhibit the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by blocking the action of LHRH on its receptors. One key aspect of LHRH antagonists is that they do not cause tumor flare, which refers to a temporary increase in hormone levels that can sometimes occur with LHRH agonists.

The correct answer identifies a characteristic that is contrary to the role of LHRH antagonists. Unlike LHRH agonists, which can promote estrogen production at the onset of treatment, LHRH antagonists do not promote the production of estrogen; instead, they suppress LH and FSH release, leading to decreased stimulation of the ovaries and testicles which ultimately reduces estrogen levels.

In terms of their mechanism of action, LHRH antagonists directly impact the hormone production in the ovaries and testicles by preventing the secretion of LH and FSH, though not through a stimulation of hormonal production. This mechanism is crucial in conditions such as hormone-sensitive cancers, where reducing estrogen levels can be beneficial for treatment. Therefore, the characteristic that LHRH antagonists promote estrogen production